Aromatizable steroids

Is it effective? How is it used? What about dosage recommendations and overall results ?   Buy legal steroids online here.

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Anabolic steroids can cause the development of acne. However, the extent to which it is experienced can be due to a number of varying factors, with the particular steroids and exact dosages used being primary. The skin´s sebaceous glands have a particularly high affinity to Dihydrotestosterone, which is an androgen the body naturally produces from testosterone via the enzyme 5-alpha Reductase. Increased sebaceous gland activity promotes oily skin which can combine with bacteria and dead skin (normal wear and tear) eventually causing pores to become clogged more quickly than the body can cleanse them. This of course, is preventable by using only particular steroids, cleansing the skin regularly, and perhaps using a topical anti-androgen.

The aim of this study was to examine the inhibitory effect of the non-aromatizable androgens on FSH-stimulated aromatase activity in porcine granulosa cells. The cells were isolated from medium-sized follicles (4-6 mm) of prepubertal pigs, and cultured under chemically defined conditions in the presence of FSH (1 microgram/ml, NIADDK-oFSH-S13) with and without the androgens for an initial 48-h induction period. Subsequently, the spent medium was replaced with fresh medium containing only testosterone as substrate and the cells were reincubated for a further 6 h. The conversion of this steroid to oestradiol-17 beta during this latter 'test' period was taken as a measure of the aromatase activity. The addition of 5 alpha-dihydrotestosterone (DHT) into cultures of FSH-stimulated cells during the induction period resulted in a definite dose-dependent inhibition (30-70%) of the aromatase activity expressed in the test period. This inhibitory action, of the mixed non-competitive type, is characterized by a decrease in the apparent Vmax and an increase in the Km value, suggestive of an androgen inhibition of FSH-stimulated aromatase synthesis. This inhibition was also shown by the other 5 alpha- and 5 beta-reduced androgens: 5 beta-androstanedione was the most effective, while DHT was the least. Other steroids such as pregnenolone and progesterone were inhibitory, but testosterone and diethylstilboestrol were stimulatory. These results suggest an important mechanism for the intrafollicular control of oestrogen synthesis, involving a possible reciprocal relationship between aromatase and 5 alpha-reductase activities.

As far as dosing is concerned, no definitive guidelines have yet been formed, although in my opinion it is likely that Ment will probably end up being dosed along the same lines as Trenbolone, with the average dose falling somewhere 200-500 mg per week. Of course, not all users will adhere to these guidelines, with some electing to administer a more hearty dosage. Overall, we are looking at a very potent steroid, both on paper and in the real-world, which is capable of eliciting serious gains in mass & strength over a relatively short period of time. As availability increases, look for this steroid to take up a more permanent residence in the arsenals of BB’rs and strength athletes alike.
 

Aromatizable steroids

aromatizable steroids

As far as dosing is concerned, no definitive guidelines have yet been formed, although in my opinion it is likely that Ment will probably end up being dosed along the same lines as Trenbolone, with the average dose falling somewhere 200-500 mg per week. Of course, not all users will adhere to these guidelines, with some electing to administer a more hearty dosage. Overall, we are looking at a very potent steroid, both on paper and in the real-world, which is capable of eliciting serious gains in mass & strength over a relatively short period of time. As availability increases, look for this steroid to take up a more permanent residence in the arsenals of BB’rs and strength athletes alike.
 

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