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Beclometasone dipropionate was first patented in 1962 and used medically in 1972. [7] It was approved for medical use in the United States in 1976. [1] It is on the World Health Organization's List of Essential Medicines , the most effective and safe medicines needed in a health system . [8] The wholesale price in the developing world for an inhaler containing 200 doses of medication is about USD as of 2014. [9] In the United States it costs between 50 and 100 USD for a typical month supply of the inhaled form. [10]

Mometasone furoate increased chromosomal aberrations in an in vitro Chinese hamster ovary-cell assay, but did not increase chromosomal aberrations in an in vitro Chinese hamster lung cell assay. Mometasone furoate was not mutagenic in the Ames test or mouse- lymphoma assay, and was not clastogenic in an in vivo mouse micronucleus assay and a rat bone marrow chromosomal aberration assay or a mouse male germ -cell chromosomal aberration assay. Mometasone furoate also did not induce unscheduled DNA synthesis in vivo in rat hepatocytes.

Nasal steroid spray brand names

nasal steroid spray brand names

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