The dose of Nystatin for children and adults is 4-6 mL four times daily (one-half of dose in each side of mouth). The preparation should be retained in the mouth as long as possible before swallowing. Infant dose is 2 mL four times daily (in infants and young children, use dropper to place one-half of dose in each side of mouth and avoid feeding for 5 to 10 minutes). Nystatin is not absorbed by the body, so drug interactions are not expected. Tell your doctor all prescription or over-the-counter medicines and supplements you use. Nystatin should be used only when prescribed during pregnancy. It is not known whether this drug passes into breast milk. Consult your doctor before breast-feeding.