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Anaphylaxis: Based on spontaneous reports and an estimated exposure of about 57,300 patients from June 2003 through December 2006, the frequency of anaphylaxis attributed to Xolair use was estimated to be at least % of patients. Diagnostic criteria of anaphylaxis were skin or mucosal tissue involvement, and, either airway compromise, and/or reduced blood pressure with or without associated symptoms, and a temporal relationship to Xolair administration with no other identifiable cause. Signs and symptoms in these reported cases included bronchospasm, hypotension, syncope, urticaria, angioedema of the throat or tongue, dyspnea, cough, chest tightness, and/or cutaneous angioedema. Pulmonary involvement was reported in 89% of the cases. Hypotension or syncope was reported in 14% of cases. Fifteen percent of the reported cases resulted in hospitalization. A previous history of anaphylaxis unrelated to Xolair was reported in 24% of the cases.

Q. My arm became limp after flu shot & have had pain in arm. Vaccine itself or improper injection? Any advice? I could not move my arm about 3 hours after the injection. It took about 3 days before I could raise my arm at all. It became painful to use and has bothered me for a couple of months. The doctor gave me a cortisone shot which helped some but not completely. He had never seen this reaction before. Is it a reaction to the vaccine or could it be the way it was injected? Is their anyone who has had or knows of a similar case? A. I had a flu shot last October, and it was given to me directly on the backside (and up high) of my shoulder. I went to the gym after I received the shot, and now have two tears in my (torn) rotator cuff, with a perforation in my rotator cuff tendon. I think it may have been improperly given. Now I need to have surgery to repair it. Look up your symptoms on webmd, and surf the net. Talk to your doctor too. The only way to find out what is really going on with it is to have an MRI. A simple xray will not reveal a tear in the muscle or tendon in the rotator cuff. If you can't lift your arm, and have trouble sleeping at night, and pain on your deltoid and bicep (rotator cuff injury pain radiates to these areas) because of the pain, then chances are you have an injured rotator cuff. These people giving these immunizations need more training. They are causing serious injury to people that go in to get a shot to stay healthy, and then end up with a serious injury, and possible surgery !!! Goo

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